

Breast cancer is the most frequently diagnosed cancer among women worldwide. In 2020 alone, more than 2.3 million new cases were reported globally, with over 685,000 deaths. While these numbers are sobering, the good news is that early detection greatly improves outcomes.
Thanks to advances in mammograms, ultrasound, and MRI technology, abnormalities are being caught earlier than ever. But detection alone isn’t enough—a biopsy is often needed to confirm whether cancer is present.
The answer depends on the type of biopsy and the patient’s risk factors. Here's what research shows:
Bottom line: Most biopsies do not result in a cancer diagnosis—but they remain essential for ruling it out.
Several factors influence whether a breast biopsy comes back positive for cancer. These include:
Breast cancer becomes more common with age. Postmenopausal women often have a higher likelihood of a positive biopsy compared to younger individuals.
If you have close relatives with breast cancer or carry BRCA1/BRCA2 mutations, you may be at higher risk. Biopsies in high-risk individuals are more likely to detect cancer.
Dense breast tissue can hide abnormalities on mammograms, increasing the chance of needing a biopsy. It can also slightly raise cancer risk.
Advanced tools like 3D mammograms and MRI improve the accuracy of detecting suspicious areas. When paired with precise biopsy techniques, they boost early detection.
A breast biopsy doesn’t automatically mean you have cancer—it’s a diagnostic tool, not a diagnosis. Most results are benign, but if cancer is found, early detection improves survival rates significantly.
Your provider will guide you through the type of biopsy that’s right for your situation and what the results mean for your care plan.
At Gregory Rhodes MD Cancer Center, we understand how stressful a potential cancer diagnosis can be. That’s why we offer:
Worried about a breast lump or abnormal imaging result? Schedule a consultation today and let our expert team support you through your next steps.